| 产品详情 |
| Edit |   |
|---|
| Product Name | DKK2, Recombinant, Human, aa34-259, His-SUMO-Tag (Dickkopf-related Protein 2) |
|---|
| Description | Purity ~90% (SDS-PAGE). Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Source: Recombinant protein corresponding to aa34-259 from human DKK2, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~41.0kD AA |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: Q9UBU2 |
|---|
| Catalog # | 373063 |
|---|
| Price | |
|---|
| Order / More Info | DKK2, Recombinant, Human, aa34-259, His-SUMO-Tag (Dickkopf-related Protein 2) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|