| 产品详情 |
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| Product Name | DKK2, Recombinant, Human, aa34-259, His-Tag (Dickkopf-related protein 2) |
| Description | Purity ~90% (SDS-PAGE). Dickkopf-related protein 2, also known as DKK2, belongs to the dickkopf family. DKK2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Source: Recombinant protein corresponding to aa34-259 of human DKK2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~27.6kD AA |
| Size | 20ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NP_055236 |
| Catalog # | 349852 |
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| Order / More Info | DKK2, Recombinant, Human, aa34-259, His-Tag (Dickkopf-related protein 2) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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