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| Product Name | Heregulin beta-2, Recombinant, Human |
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| Description | Purity ~95% (RP-HPLC and SDS-PAGE). Neuregulin is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells, playing an important role in heart structure and function through inducing ErbB2/ErbB4 receptor phosphorylation and cardiomyocyte differentiation. Research on molecular level discovered that neuregulin recombinant could make disturbed myocardial cell structure into order and strengthen the connection between myocardial cells by intercalated discs re-organization. Pharmacodynamic experiments in animals showed that neuregulin (NRG1) recombinant can reduce the degree of damage on myocardial cells caused by ischemia, hypoxia and viral infection. Source: Recombinant corresponding to human Heregulin-B2, expressed in E.coli. Molecular Weight: ~7kD Biological Activity: The ED50, calculated by the dose-dependant stimulation of human MCF-7 cells is 2x10e6units/mg. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Heregulin beta-2, Recombinant, Human (NRG1, Pro-neuregulin-1, Membrane-bound Isoform, Pro-NRG1, Neuregulin-1, Acetylcholine Receptor-inducing Activity, ARIA, Breast Cancer Cell Differentiation Factor p45, Glial Growth Factor, Heregulin, HRG, Neu Differentiation Factor, Sensory and Motor Neuron-derived Factor, GGF, HGL, HRGA, NDF, SMDF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 136907 |
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| Order / More Info | Heregulin beta-2, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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