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| Product Name | BCRP Inhibitor III, YHO-13177 |
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| Description | Purity ~98% (HPLC). A cell-permeable acrylonitrile compound that potently inhibits breast cancer resistance protein (BCRP/ABCG2)-mediated drug export and reverses BCRP-mediated drug resistance in vitro (half maximal in the range 0.01-1uM) without altering the BCRP expression levels (in 10uM in A549 cells). An in vivo bioavailable and readily water soluble prodrug of YHO-13177, BCRP Inhibitor IV, YHO-13351 is also available. Formula: C20H22N2O3S Molecular Weight: 370.5 Solubility: DMSO (100mg/ml) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BCRP Inhibitor III, YHO-13177 ((Z)-2-(3,4-Dimethoxyphenyl)-3-(5-(4-hydroxypiperidin-1-yl)thiophen-2-yl)acrylonitrile) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217211 |
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| Order / More Info | BCRP Inhibitor III, YHO-13177 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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