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ERN1, Recombinant, Human, GST-Tag (Endoplasmic Reticulum-to-Nucleus Signaling 1, hIRE1p, IRE1, IRE1A, IRE1P) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | ERN1, Recombinant, Human, GST-Tag (Endoplasmic Reticulum-to-Nucleus Signaling 1, hIRE1p, IRE1, IRE1A, IRE1P) |
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| Description | Purified (~70-90%). ERN1 or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals. ERN1 controls IRE1 proteolysis in mammalian cells. The activation of ERN1 through oligomerization expands the mechanistic repertoire of kinase-based signaling receptors. ERNI has a critical function in extraembryonic cells that is essential for fetal viability. Source: Recombinant protein corresponding to human ERN1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~87kD Specific Activity: 55nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001433 |
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| Catalog # | 499976 |
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| Price | |
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| Order / More Info | ERN1, Recombinant, Human, GST-Tag (Endoplasmic Reticulum-to-Nucleus Signaling 1, hIRE1p, IRE1, IRE1A, IRE1P) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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