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| Product Name | Plasmin, Human (Agarose) |
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| Description | Plasmin is a serine protease with broad specificity which, in addition to cleavage of fibrin, is capable of activation and/or degradation of compounds of the coagulation, kinin generation and complement systems. Although plasmin can be inhibited by a number of plasma protease inhibitors in vitro, regulation of plasmin in vivo is thought to occur mainly through its interaction with a2-antiplasmin, and to a lesser extent, a2-macroglobulin. Human Lys-plasmin is immobilized on agarose resin by coupling of primary amines. Plasmin retains catalytic activity when coupled and may be used to efficiently activate single-chain tissue-type plasminogen activator tPA and uPA to the two-chain form(1). It may also be used to convert plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids. |
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| Size | 1ml |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P4256-02A |
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| Order / More Info | Plasmin, Human (Agarose) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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