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| Product Name | PD-1 (Biotinylated) : PD-L1 Inhibitor Screening BioAssay™ Kit |
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| Description | Cell signaling through the PD-1 receptor upon binding the PD-L1 ligand attenuates immune responses and is exploited by both tumors and viruses. The PD-L1 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. This kit comes in a convenient 96-well format, with biotin-labeled PD-1, purified PD-L1, streptavidin-labeled HRP, and assay buffer for 100 binding reactions. The key to this kit is the high sensitivity of detection of biotin-labeled PD-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-L1 is coated on a 96-well plate. Next, PD-1 is incubated with PD-L1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader. Applications: This kit is most useful for screening for inhibitors of PD-L1. Components: PD-1, Biotin-labeled, 1x5ug PD-L1, 1x100ug Stre |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 171952 |
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| Order / More Info | PD-1 (Biotinylated) : PD-L1 Inhibitor Screening BioAssay™ Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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