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| Product Name | CD40L, BioAssay™ ELISA Kit (Mouse) (CD40 Ligand) |
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| Description | CD40 ligand (CD40L) is a type II membrane protein of 261aa on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumor necrosis factor- alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb/IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 21947, SwissProt: P27548 |
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| Catalog # | 352766 |
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| Order / More Info | CD40L, BioAssay™ ELISA Kit (Mouse) (CD40 Ligand) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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