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| Product Name | Nlrp3, Recombinant, Mouse, aa1-153, His-SUMO-Tag (NACHT, LRR and PYD Domains-containing Protein 3) |
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| Description | Purity ~90% (SDS-PAGE). May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA (By similarity). Activates caspase-1 as part of the NALP3 inflammasome complex in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Source: Recombinant protein corresponding to aa1-153 from mouse Nlrp3, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~34.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cold autoinflammatory syndrome 1 protein homolog, Cryopyrin Mast cell maturation-associated-inducible protein 1, PYRIN-containing APAF1-like protein 1 |
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| Gene, Accession, CAS # | SwissProt: Q8R4B8 |
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| Catalog # | 374429 |
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| Order / More Info | Nlrp3, Recombinant, Mouse, aa1-153, His-SUMO-Tag (NACHT, LRR and PYD Domains-containing Protein 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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