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| Product Name | DLL4, Recombinant, Mouse,Fc (Delta-like Protein 4, Delta4) |
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| Description | Purity ≥90% (SDS-PAGE). Endotoxin: ≤0.1EU/ug purified protein (LAL method). The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina. Biological Activity: Inhibits adipogenesis of 3T3L-1 cells. Sequence: Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Delta-like Protein 4, Delta4 |
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| Gene, Accession, CAS # | SwissProt: Q9JI71 |
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| Catalog # | 44755 |
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| Order / More Info | DLL4, Recombinant, Mouse,Fc (Delta-like Protein 4, Delta4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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