| 产品详情 |
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| Product Name | ZM-336372 |
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| Description | MW: 513.6. Purity ≥98% (TLC; 5% CH3OH in CH2Cl2; Rf=0.43); NMR (conforms). c-Raf inhibitorPotent, competitive dual site (ATP- and substrate-binding domains) Src and Lck inhibitor (IC50 = 44 and 88 nM respectively). Also inhibits VEGFR2 and c-fms at higher concentrations (IC50 = 0.32 and 30 uM respectively).Scientific Background: Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50uM |
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| Size | 1 mg, 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Src-I1; 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine; 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]-benzamide] |
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| Gene, Accession, CAS # | CAS: 208260-29-1.Molecular |
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| Catalog # | MBS515008 |
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| Order / More Info | ZM-336372 from MYBIOSOURCE INC. |
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| Product Specific References | 1. Tian et al. Biochem. 2001 40:7084 2. J Bain et al. Biochem. J. 2007 408:297 |
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