| 产品详情 |
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| Product Name | ZM-447439 |
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| Description | MW: 513.6. Purity >98% (TLC); NMR (Conforms). JAK-2 inhibitorScientific Background: Novel, selective ATP-competitive inhibitor of Aurora B kinase in vitro (IC50 values are 50, 250 and 1000 nM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC50 > 10 uM). Inhibits cell division and displays selective toxicity towards proliferating tumor cells versus non-dividing cells. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Dorsomorphin; (N-[4-[[6-Methoxy-7-[3-(4-morpholinyl) propoxy]-4-quinazolinyl] amino] phenyl] benzamide] |
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| Gene, Accession, CAS # | CAS: 331771-20-1 |
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| Catalog # | MBS515065 |
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| Order / More Info | ZM-447439 from MYBIOSOURCE INC. |
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| Product Specific References | 1. C Ditchfield et al J. Cell Biol. 2003 161:267 2. F Girdler et al J. Cell Sci. 2006 119:3664 3. F H Jung et al J. Med. Chem. 2006 49:955 |
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