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| Product Name | Adrenergic Receptor, beta 3, Human (Control Peptide) (B3AR, BAR3, ADRB3R, Beta-3 adrenoreceptor) |
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| Description | Highly purified. Control Peptide for A0906-91 (antiserum) and A0906-91A (affinity purified antibody). The beta 3-adrenergic receptor (B3AR) is a member of the super-family of G protein-coupled receptor superfamily. They are characterized by seven putative transmembrane helices connected by hydrophilic loops. The mechanism by which the activated beta ARs transmit the signals across the plasma membrane involves the stimulation of Gs. This stimulation in turn activates adenyl cyclase. Activation of adenyl cyclase yields the second messenger cAMP. B3AR is primarily present in adipocytes The B3AR plays a significant role in the control of lipolysis and thermogenesis in the brown adipose tissue of rodents and humans. In humans, B3AR, a Trp to Arg replacement has recently been discovered at position 64. This change in the first coding exon has been correlated with increased weight gain, difficulty in losing weight, insulin resistance syndrome, and worsened diabetic situation. Higher percentag |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A0906-94 |
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| Order / More Info | Adrenergic Receptor, beta 3, Human (Control Peptide) (B3AR, BAR3, ADRB3R, Beta-3 adrenoreceptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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