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| Product Name | PDK1, Recombinant Human |
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| Description | Purified: ≥95% by SDS-PAGE. PDK1 (pyruvate dehydrogenase kinase isoform 1) is involved in the regulation of enzymatic activity of mammalian pyruvate dehydrogenase (PDH) that is a part of a mitochondrial multienzyme complex to catalyze the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. PDK1 has been found to serve as an effective therapeutic target for inhibition of glioblastoma growth. Recombinant human PDK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Source: Human, His-tagged, Recombinant, E. coli, 29-436aa AA Sequence: MGSSHHHHHH SSGLVPRGSH MSSDSGSSPA SERGVPGQVD FYARFSPSPL SMKQFLDFGS VNACEKTSFM FLRQELPVRL ANIMKEISLL PDNLLRTPSV QLVQSWYIQS LQELLDFKDK SAEDAKAIYD FTDTVIRIRN RHNDVIPTMA QGVIEYKESF GVDPVTSQNV QYFLDRFYMS RISIRMLLNQ HSLLFGGKGK GSPSHRKHIG SINPNCNVLE VIKDGYENAR RLCDLYYINS PELELEELNA KSPGQPIQVV |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PDK1, Recombinant Human (PDPK1, PI-P3 Dependent Kinase, 3a Phosphoinositide dependent Protein Kinase 1) |
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| Gene, Accession, CAS # | Accession: NP_002601 |
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| Catalog # | P3123-02E |
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| Order / More Info | PDK1, Recombinant Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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