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| Product Name | Pdk3, Recombinant, Mouse, aa131-362, His-tag |
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| Description | Purity ~90% (SDS-PAGE). Pdk3, Recombinant, Mouse, aa131-362, His-Tag ([Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 3, Mitochondrial). Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species. Source: Recombinant protein corresponding to aa131-362 from mouse Pdk3, fused to His-Tag at N-terminal expressed in E. coli. Molecular Weight: ~30.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Pyruvate dehydrogenase kinase isoform 3 |
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| Gene, Accession, CAS # | SwissProt: Q922H2 |
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| Catalog # | 374649 |
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| Price | |
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| Order / More Info | Pdk3, Recombinant, Mouse, aa131-362, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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