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| Product Name | Recombinant Human Apoptosis-inducing factor 1, mitochondrial |
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| Description | 103-612aa; Partial. MW: 71.5kD. Purity >90% as determined by SDS-PAGE. Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nuc |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Programmed cell death protein 8] |
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| Gene, Accession, CAS # | AIFM1, Gene ID: 9131, Accession: NP_001124318.2 |
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| Catalog # | MBS1015301 |
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| Order / More Info | Recombinant Human Apoptosis-inducing factor 1, mitochondrial from MYBIOSOURCE INC. |
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| Product Specific References | Molecular characterization of mitochondrial apoptosis-inducing factor.Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Snow B.E., Brothers G.M., Mangion J., Jacotot E., Costantini P., Loeffler M., Larochette N., Goodlett D.R., Aebersold R., Siderovski D.P., Penninger J.M., Kroemer G.Nature 397:441-446(1999) |
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