| 产品详情 |
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| Product Name | Recombinant Human APP / Protease nexin-II Protein (Fc tag) |
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| Description | MW: 84,521 Da. Purity >95 % as determined by SDS-PAGE. Background: Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can be processed by two different proteolytic pathways. In one pathway, APP is cleaved by beta- and gamma-secretase to produce the amyloid-beta-protein (Abeta, Abeta, beta-amyloid) which is the principal component of |
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| Size | 0.01 mg, 0.02 mg |
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| Concentration | n/a |
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| Applications | The recombinant human APP/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 890 amino acids and predicts a molecular mass of 101 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhAPP/Fc monomer is approximately 150-160 kDa due to the glycosylation. |
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| Other Names | [AAA, APP, ABETA, ABPP, AD1, APPI, CTF gamma, CVAP, PN2] |
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| Gene, Accession, CAS # | APP, Gene ID: 351, Accession: NP_958816.1 |
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| Catalog # | MBS2546122 |
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| Price | |
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| Order / More Info | Recombinant Human APP / Protease nexin-II Protein (Fc tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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