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| Product Name | Filamentous Hemagglutinin (FHA) |
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| Description | Band representing 84% of the protein when examined on 4-12% SDS-polyacrylamide gels. The initial step in establishing a Bordetella pertussis infection is attachment of the bacteria to the epithelial lining of the host respiratory tract. Two B. pertussis virulence factors are key in this process, filamentous hemagglutinin (FHA) and fimbriae (Fim). FHA , which is both surface- associated and secreted by B. pertussis, is a multifunctional protein which promotes the attachment of the bacteria through several binding domains. Because FHA is highly immunogenic, it is included in many of the acellular vaccines. Additionally, FHA acts through multiple pathways to modulate the host immune response; an example of this type of activity is suppression of the development of the host IL-17-mediated inflammatory response. FHA is a large, 220kD beta-helical protein which is isolated from the native Bordetella pertussis strain 165. Source: Filamentous Hemagglutinin, strain 165 from B. pertussis. Molecu |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 215941 |
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| Order / More Info | Filamentous Hemagglutinin (FHA) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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