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| Product Name | Cobra Venom Factor, Recombinant, Naja Kaouthia, aa733-984, GST-Tag |
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| Description | Purity ~90% (SDS-PAGE). Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity. Source: Recombinant protein corresponding to aa733-984 from naja kaouthia Cobra venom factor, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~55.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Complement C3 homolog |
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| Gene, Accession, CAS # | SwissProt: Q91132 |
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| Catalog # | 372816 |
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| Order / More Info | Cobra Venom Factor, Recombinant, Naja Kaouthia, aa733-984, GST-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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