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| Product Name | Cytokeratin 8, Recombinant, Human |
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| Description | Purity > 95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. Endotoxin: ≤ 0.1ng/ug (IEU/ug). Keratins are a class of fibrous proteins or scleroproteins important both as structural proteins and as keys to the study of protein conformation. The family represents the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix of tooth enamel. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms an alpha-helix, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. Keratin 8 is a major component of intermediate filaments in single-layered epithelia of the gastrointestinal tract. Keratin 8 deficient mice display signs of colitis and diarrhoea characteristic for inflammatory bowel disease. Recombinant Human Cytokeratin 8 is a single, non-glycosylated polypeptide chain having a molecular mass of 53.53kD Dimers and Aggregates: ≤ 1% as determined by si |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C9097-42R |
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| Order / More Info | Cytokeratin 8, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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