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| Product Name | CD14, Recombinant, Human |
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| Description | Highly Purified (~95%). CD14 is an ~50kD cell surface glycoprotein that is preferentially expressed on monocytes/macrophages. The human CD14 cDNA encodes a 375aa residue precursor protein with a 19aa signal peptide and a C-terminal hydrophobic region characteristic for glycosylphosphatidyinositol (GPI)-anchored proteins. Human CD14 has four potential N-linked glycosylation sites and also bears O-linked carbohydrates. The amino acid sequence of human CD14 is ~65% identical with the mouse, rat, rabbit, and bovine proteins. CD14 is a pattern recognition receptor that binds lipopolysaccharides (LPS) and a variety of ligands derived from different microbial sources. The binding of CD14 with LPS is catalyzed by LPS-binding protein (LBP). Source: Recombinant protein corresponding to human CD14, expressed in CHO cells. Molecular Weight: ~50kD Biological Activity: Up to 20ug/ml CD14 inhibits binding of LPS (FITC) (0.5ug/ml) to 6x10e5 CD14+CHO transfectants (FACS). Applications: Suitable for use |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | CD14, Recombinant, Human (Monocyte Differentiation Antigen CD14, Myeloid Cell-Specific Leucine-Rich Glycoprotein) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299332 |
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| Order / More Info | CD14, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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