| 产品详情 |
| Edit |   |
|---|
| Product Name | CD14, Recombinant, Human |
|---|
| Description | Purity ~90-95% (SDS-PAGE). CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocytes, macro pha ges and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50kD protein. Source: Recombinant corresponding to human CD-14, expressed in CHO cells. Molecular Weight: ~50kD Biological Activity: Inhibits binding of LPS to CD14. Upto to 20ug/ml CD14 inhibit binding of FITC-LPS (0.5ug/ml) to 6x10e5 CD14+CHO transfectants (FACS) Endotoxin: <0.01ng/ml |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | CD14, Recombinant, Human (Monocyte Differentiation Antigen CD14, Myeloid Cell-specific Leucine-rich Glycoprotein) |
|---|
| Gene, Accession, CAS # | SwissProt: P08571 |
|---|
| Catalog # | C2265-37 |
|---|
| Price | |
|---|
| Order / More Info | CD14, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|