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| Product Name | CD157, Recombinant, Human |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin ≤ 1EU. CD157, also known as bone marrow stromal cell antigen 1 (BST-1), is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family (1). CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth (2, 3). Along with CD38, CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities (2). It may play a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derived bone marrow stromal cell lines (3). CD157 has been predicted to function as a cell surface receptor and an immunoregulatory molecule (4). Source: Recombinant human CD157 encoded by the BST-1 gene (rhCD157; aa29 to 292; GARARWRGEGT. Accession # Q10588) was expressed with a C-terminal 6X His tag in a murine myeloma cell line, NS0. Definition: Measured by its ability to cyclize nicotinamide guanine dinucleotide ( |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q10588 |
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| Catalog # | C2548-86H |
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| Order / More Info | CD157, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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