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| Product Name | SETD1A (KMT2F), Active |
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| Description | 1418-end. MW: 61 kDa. Description: Recombinant human SETD1A (1418-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: As a member of the mixed lineage leukemia (MLL) family of histone methyltransferase, it specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenet |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Methyltransferase Assay |
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| Other Names | [Homo sapiens SET domain containing 1A (SETD1A), mRNA; Histone-lysine N-methyltransferase SETD1A; histone-lysine N-methyltransferase SETD1A; SET domain containing 1A; Lysine N-methyltransferase 2F; SET domain-containing protein 1A; hSET1A; Set1/Ash2 histone methyltransferase complex subunit SET1] |
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| Gene, Accession, CAS # | SETD1A, Gene ID: 9739, Accession: NM_014712.2 |
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| Catalog # | MBS515668 |
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| Order / More Info | SETD1A (KMT2F), Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Li Y, et al: Structural basis for activity regulation of MLL family methyltransferases. Nature. 530 (7591):447-52. 2016 2. http://www.uniprot.org/uniprot/O15047 |
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