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| Product Name | SETDB1 (KMT1E) Protein |
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| Description | 715-end. MW: ~100 kDa. Description: Recombinant human SETDB1 (KMT1E) (715-end) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: Histone-lysine N-methyltransferase SETDB1 (SETD6) specifically trimethylates 'Lys-9' of histone H3 and plays a central role in the silencing of euchromatic genes. SETDB1 is targeted to histone H3 by TRIM28/TIF1B, a factor recruited by KRAB zinc-finger proteins. Required for activated KRAS-mediated promoter hypermeth |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Methyltransferase Assay |
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| Other Names | [Homo sapiens SET domain, bifurcated 1, mRNA; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase SETDB1; SET domain bifurcated 1; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1] |
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| Gene, Accession, CAS # | SETDB1, Gene ID: 9869, Accession: BC028671 |
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| Catalog # | MBS515672 |
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| Order / More Info | SETDB1 (KMT1E) Protein from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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