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| Product Name | SETDB2 Recombinant protein |
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| Description | MW: ~120 kDa. Recombinant full-length human SETDB2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: SETDB2 is a histone H3 methyltransferase that modulates gene expression epigenetically through histone H3 methylation. Methylation of histone H3 at lysine 9 (H3K9) by SETDB2 has emerged as an important player in the formation of heterochromatin, chromatin condensation, and transcriptional repression. SETDB2 is recruited to heterochr |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [CLLD8; CLLL8] |
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| Gene, Accession, CAS # | SETDB2, Gene ID: 83852, Accession: BC047434 |
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| Catalog # | MBS515393 |
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| Order / More Info | SETDB2 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Falandry C. et al: CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregation. J Biol Chem. 2010 Jun 25;285(26):20234-41. 2. Zhang, Y. et al: Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nature Genet. 34: 181-186, 2003. |
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