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| Product Name | Radius 24-Well Cell Migration Assay |
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| Description | Background: Cell migration is a highly integrated, multistep process that orchestrates embryonic morphogenesis, tissue repair and regeneration. It plays a pivotal role in the disease progression of cancer, mental retardation, atherosclerosis, and arthritis. The initial response of a cell to a migration-promoting agent is to polarize and extend protrusions in the direction of the attractant; these protrusions can consist of large, broad lamellipodia or spike-like filopodia. In either case, these |
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| Size | 24 assays, 120 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168756 |
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| Order / More Info | Radius 24-Well Cell Migration Assay from MYBIOSOURCE INC. |
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| Product Specific References | 1. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. (2003) Science 302, 1704-9.2. Horwitz R, Webb D. (2003) Curr Biol. 13, R756-9.3. Lauffenburger DA, Horwitz AF. (1996) Cell 84, 359-369.1. Langfelder, A. et al. (2015). Extracellular acidosis impairs P2Y receptor-mediated Ca 2 signalling and migration of microglia. Cell Calcium. doi: 10.1016/j.ceca.2015.01.004.2. Cersosimo, E. et al. (2014). Acute insulin resistance stimulates and insulin sensitization attenuates vascular smooth muscle cell migration and proliferation. Physiol Rep. 2:e12123.3. Qiang, L. et al. (2014). Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A. 111:9241-9246.4. Sriram, S. et al.(2013). Triple combination of siRNAs targeting TGFbeta1, TGFbetaR2, and CTGF enhances reduction of collagen I and smooth muscle actin in corneal fibroblasts. Invest. Opthalmol. Vis. Sci. 54:8214-82235. Robinson, P. et al. (2013). MicroRNA signature in wound healing following excimer laser ablation: role of miR-133b on TGFbeta1, CTGF, SMA, and COL1A1 expression levels in rabbit corneal fibroblasts. J. Cell Sci. 126:4769-4781.6. Sun, J. et al. (2013). Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway. Mol. Pharmacol. 83:454-469.7. Apostolos, K. et al. (2013). Increased susceptibility of melanin-concentrating hormone-deficient mice to infection with Salmonella enterica Serovar typhimurium. Infect. Immun. 81: 166-172.8. Smith, K. et al. (2012). Human Family with Sequence Similarity 60 Member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex. Mol. Cell. Proteomics. 11:1815-1828.9. Chuang, T.D. et al. (2012). miR-93/106b and their host gene, MCM7, are differentially expressed in leiomyomas and functionally target F3 and IL-8. Mol. Endocrin. 26: 1028-1042.10. Young, S. et al. (2012). Rapid Protein Kinase D1 signaling promotes migration of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 303: G356-G366.11. Larive, R.M. et al. (2012). The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development. Mol. Biol. Cell. 23:2373-2387 |
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