| 产品名称 |
PPM1F, Recombinant, Human, His-Tag (Protein Phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | PPM1F, Recombinant, Human, His-Tag (Protein Phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2) |
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| Description | Purity ~90% (SDS-PAGE). PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. Recombinant human PPM1F protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa1-454 and 477aa of human PPM1F, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~52kD Specific Activity: >1200unit/mg. Enzymatic activity was confirmed by measuring the amount of enzyme hydrolyzing 1nmole of p-nitrophenyl phosphate (pNPP) per minute at 37°C, pH 7.5 using 10m |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | PPM1F, Gene ID: 9647, SwissProt: P49593 |
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| Catalog # | 301268 |
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| Order / More Info | PPM1F, Recombinant, Human, His-Tag (Protein Phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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