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| Product Name | Recombinant Human S-phase kinase-associated protein 1 |
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| Description | 2-163aa; Full Length. MW: 34.52kD. Purity >90% as determined by SDS-PAGE. Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cyclin-A/CDK2-associated protein p19; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B; p19A; p19skp1 ] |
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| Gene, Accession, CAS # | SKP1, Gene ID: 6500, Accession: NP_008861.2 |
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| Catalog # | MBS953870 |
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| Order / More Info | Recombinant Human S-phase kinase-associated protein 1 from MYBIOSOURCE INC. |
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| Product Specific References | p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase.Zhang H., Kobayashi R., Galaktionov K., Beach D.Cell 82:915-925(1995) A novel cDNA with homology to an RNA polymerase II elongation factors maps to human chromosome 5q31 (TCEB1L) and to mouse chromosome 11 (Tceb1l).Sowden J., Morrison K., Schofield J., Putt W., Edwards Y.Genomics 29:145-151(1995) |
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