| 产品详情 |
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| Product Name | Recombinant Human S-phase kinase-associated protein 2 |
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| Description | 1-424aa; Full Length. MW: 63.73kD. Purity >90% as determined by SDS-PAGE. Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Reco |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cyclin-A/CDK2-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; p45skp2 ] |
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| Gene, Accession, CAS # | SKP2, Gene ID: 6502, Accession: NP_001230049.1 |
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| Catalog # | MBS1381057 |
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| Order / More Info | Recombinant Human S-phase kinase-associated protein 2 from MYBIOSOURCE INC. |
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| Product Specific References | p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase.Zhang H., Kobayashi R., Galaktionov K., Beach D.Cell 82:915-925(1995) Human SKP2-like protein.Yamaguchi T. Androgenic regulation of Skp2 in androgen-dependent and -independent LNCaP human prostate tumor cells.Kokontis J.M., Fukuchi J., Liao S. Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., N |
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