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| Product Name | CBX7, Recombinant, Human, aa1-251, His-Tag (Chromobox Protein Homolog 7) |
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| Description | Purity ~90% (SDS-PAGE). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. Source: Recombinant protein corresponding to aa1-251 from human CBX7, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~30.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O95931 |
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| Catalog # | 372610 |
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| Order / More Info | CBX7, Recombinant, Human, aa1-251, His-Tag (Chromobox Protein Homolog 7) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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