| 产品详情 |
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| Product Name | Exchange Inhibitor Peptide, Rat (XIP) (Control Peptide) |
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| Description | Highly purified. The 20aa Peptide (designated XIP11-P; control peptide) corresponding to rat XIP. The 20 AA rat is 100% conserved in mouse, rat, human, rabbit, frog NCX1. Ca2+ plays a critical role in intracellular signaling. Intracellular Ca2+ levels are tightly controlled by continuos removal of Ca2+ via ATP-driven Ca2+ pump in the endoplasmic reticulum and plasma membrane, and Ca2+ transport system, the Na+/Ca2+ exchangers (NCX), in the plasma membrane. NCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In most cells, 3 Na+ are exchanged for 1 Ca2+. In mammals, at least 5 distinct genes code for the exchangers: Three NCX (NCX1, NCX2, and NCX3), and two in the NCKX family (NCKX1 and NCKX2). NCX share significant sequence homology (~70%), display 11 TM domains, a large central, intracellular hydrophilic regulatory loop between TM5 and 6, extracellular N-terminus and cytoplasmic C-terminus. The N-terminal signal peptide i |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E9004-50 |
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| Order / More Info | Exchange Inhibitor Peptide, Rat (XIP) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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