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| Product Name | Neuropoietin, Recombinant, Mouse (NPO, NP) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex comprising CNTF receptor-a component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human Neuropoietin gene has evolved toward a pseudogene, suggesting that the alternative signaling via CNTF is an effective compensatory pathway.Recombinant murine Neuropoietin is a 19.8kD protein containing 183 amino acid residues. Biological Activity: The ED50 was |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143448 |
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| Order / More Info | Neuropoietin, Recombinant, Mouse (NPO, NP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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