| 产品详情 |
| Edit |   |
|---|
| Product Name | Neuroprotectant, OBA-09 (2-(2-Oxopropanoyloxy)Benzoic Acid) |
|---|
| Description | Purity ~99% (HPLC). A brain-permeable ester of pyruvate and salicylic acid that exhibits anti-oxidative and anti-excitotoxic properties. Following its uptake by the brain tissue, it releases pyruvate and salicylic acid via ester hydrolysis (t1/2 of 43 min in serum). Exerts strong neuroprotective effects in the post-ischemic brain and significantly reduces infarct volume (27% and 65% reduction in 6 and 12 hours following i.v. administration of 10mg/kg in a rat model). Also, blocks Zn2+-induced neuronal cell death. Its neuroprotective effects are attributed to its ability to prevent NAD- and ATP-depletion in post-ischemic brain and suppression of NF-kB activity by reducing IkB-a degradation. Formula: C10H8O5 Molecular Weight: 208.2 Solubility: DMSO (50mg/ml) |
|---|
| Size | 25mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 217585 |
|---|
| Price | |
|---|
| Order / More Info | Neuroprotectant, OBA-09 (2-(2-Oxopropanoyloxy)Benzoic Acid) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|