| 产品详情 |
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| Product Name | MCG10 |
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| Description | Highly Purified. C-NGSKKAERQKFSPY, from the C-Terminus of human PCBP4. Control peptide corresponding to polyclonal antibody, Catalog#M2662-01C, goat x human. MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified. Applications: Suitable for use in ELISA. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | MCG10 (PCBP4, Alpha-CP4, LIP4, Poly(rC)-Binding Protein 4, LIP4, LYST- interacting protein, RNA binding protein MCG10, alphaCP-4 protein, poly(rC)-binding protein 4, alpha CP-4) (Control Peptide) |
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| Gene, Accession, CAS # | Accession: NP_065151.1; NP_127501.1; NP_127502.1; NP_127503.1 |
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| Catalog # | M2662-01C-P |
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| Order / More Info | MCG10 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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