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| Product Name | Growth Hormone Binding Protein, Human, Recombinant (GHR, GHBP, GH receptor, Somatotropin receptor) |
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| Description | Purity ≥ 98.0% as determined by RP-HPLC, Anion-exchange FPLC. Analysis by reducing and non-reducing SDS-PAGE Silver Stained. GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. Growth Hormone Binding Protein Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and having a molecular mass of 28,107.01D. GHR is purified by proprietary chromatog |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G9000-13 |
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| Order / More Info | Growth Hormone Binding Protein, Human, Recombinant (GHR, GHBP, GH receptor, Somatotropin receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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