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| Product Name | CSK, Recombinant, Human, GST-Tag (C-Terminal Src kinase) |
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| Description | Purified (~70-90%). CSK is a cytoplasmic tyrosine kinase that has been shown to downregulate the tyrosine kinase activity of the c-src through tyrosine phosphorylation of the c-src C-terminal. A yeast 2-hybrid system has been used to identify proteins associated with CSK. The Src homology-3 (SH3) domain of CSK associates with a proline-rich region of PEP, a protein-tyrosine phosphatase expressed in hemopoietic cells. This association is highly specific and it is speculated that PEP may be an effector and/or regulator of CSK in T cells and other hemopoietic cells. Source: Recombinant protein corresponding to human CSK fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~78kD Specific Activity: 425nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_004383 |
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| Catalog # | 499902 |
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| Order / More Info | CSK, Recombinant, Human, GST-Tag (C-Terminal Src kinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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