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| Product Name | MAPT, Recombinant, Rhesus macaque, aa2-459, His-SUMO-Tag (Microtubule-associated Protein Tau) |
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| Description | Purity ~90% (SDS-PAGE). Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminal binds axonal microtubules while the N-terminal binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Source: Recombinant protein corresponding to aa2-459 from rhesus macaque MAPT, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~63.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau |
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| Gene, Accession, CAS # | SwissProt: P57786 |
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| Catalog # | 374153 |
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| Order / More Info | MAPT, Recombinant, Rhesus macaque, aa2-459, His-SUMO-Tag (Microtubule-associated Protein Tau) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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