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| Product Name | E-Cadherin BioAssay™ ELISA Kit (Rat) |
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| Description | Cadherin-1, also known as CAM 120/80 or epithelial cadherin (E-cadherin) or uvomorulin, is a protein that in humans is encoded by the CDH1 gene. E-cadherin is a Ca(2+)-dependent epithelial cell-cell adhesion molecule. Downregulation of E-cadherin expression often correlates with strong invasive potential and poor prognosis of human carcinomas. The gene spans a region of approximately 100kb, and its location on chromosome 16q22.1. It contains 16 exons and a 65-kb-long intron 2. E- cadherin gene mutations may contribute to the development of diffusely growing gastric carcinomas. It plays a central part in the process of epithelial morphogenesis and acts as a strong invasion suppressor in experimental tumor cell systems. The standard product used in this kit is recombinant gene expression with the molecular mass of 120kD. Sample Type: Cell culture supernates, serum, plasma (Heparin) Intended Use: Sandwich High Sensitivity BioAssay™ ELISA kit for Quantitative Detection of Rat E-Cadherin. S |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9R0T4 |
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| Catalog # | 396634 |
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| Order / More Info | E-Cadherin BioAssay™ ELISA Kit (Rat) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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