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| Product Name | CEACAM 6, Recombinant, Human (Carcinoembryonic Antigen Related Cell Adhesion Molecule) |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE and visualized by silver stain. Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM-6), previously called nonspecific crossreacting antigen (NCA) or CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily (1-4). In humans, CEACAMs include type I transmembrane proteins (CEACAM-1, -3, and -4) and GPI-linked molecules (CEACAM-5 through -8) (1). There is no human CEACAM-2. Human CEACAM-6 is a 90 kD, GPI-linked membrane protein that contains a 34 amino acid (aa) signal sequence, a 286 aa extracellular domain (ECD), and a 24 aa hydrophobic C-terminal propeptide. The GPI membrane anchor is attached at the C terminus following cleavage of the propeptide. CEACAM-6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains (2-4). It shows considerable glycosylation, including (sialyl) Lewis X , which mediates binding to E-selectin, galectins and some bacterial fimbrae (1, |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q53XP7 |
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| Catalog # | C2589-79C |
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| Order / More Info | CEACAM 6, Recombinant, Human (Carcinoembryonic Antigen Related Cell Adhesion Molecule) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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