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| Product Name | AHCY, aa1-432, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). AHCY, also known as adenosylhomocysteinase, is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). It regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia, a rare disease affecting brain development and muscle strength. Down-regulation of AHCY is also associated with certain forms of cancer, Huntington's disease and Wilson's disease. Source: Recombinant corresponding to aa1-432 of human AHCY, fused to His-tag at N-terminus, expressed in E.coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MSDKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMRERYS ASKPLKGARI AGCLHMTVET AVLIETLVTL GAEVQWSSCN IFSTQDHAAA AIAKAGIPVY AWKGETDEEY LWCIEQTLYF KDGPLNMILD DGGDLTNLIH TKYPQLLPGI RGISEETTTG VHNLYKMMAN ILKVPAINV NDSVTKSKFD NLYGCRESLI DGIKRATDVM IAGKVAVVAG YGDVGKGCAQ ALRGFG |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AHCY, aa1-432, Recombinant, Human (Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, SAHH) |
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| Gene, Accession, CAS # | Accession: NP_000678 |
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| Catalog # | A1059-73T |
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| Order / More Info | AHCY, aa1-432, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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