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| Product Name | Core Binding Factor alpha 1, Mouse, Control Peptide (CBFA1) |
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| Description | BMPs are important regulators of key events in the processes of bone formation during embryogenesis, postnatal growth, remodeling and regeneration of the skeleton. The BMPs function by binding to a receptor complex that is found on all normal cells and is composed of type-I and -II receptors. The primary unit of bone formation is osteoblast, the bone forming cell. These osteoblast cells respond to physical loading by transducing signals that alter gene expression patterns. Cbfa (core binding factor), the osteoblast specific transcription factor plays an important role in osteoblast differentiation and function. Cbfa1 / Runx2 / OSF2 (alternatively spliced form 507aa and 522aa in human (chr 6p21) and 528aa or 596aa in mouse) is expressed in bone thymus, testis but not in brain, lung, heart or kidney. It is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis, essential for the maturation of osteoblasts and both intramembranous and endochondral ossifi |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C7900-71C |
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| Order / More Info | Core Binding Factor alpha 1, Mouse, Control Peptide (CBFA1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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