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| Product Name | Syntaxin 4, Recombinant, Human, aa1-183 (NY-REN-31, p35-2, STX4) |
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| Description | Purity ~95% (SDS-PAGE). Syntaxin 4 (STX4) is a widely expressed type IV transmembrane protein that is a member of the syntaxin family of tSNARE (targetSoluble NSF [Nethylmaleimidesensitive factor] Attachment REceptor) membrane fusion proteins (1, 2). For membrane fusion, VAMPs (VesicleAssociated Membrane Proteins, also called Synaptotagmins) as vSNAREs on donor (vesicle) membranes interact with tSNAREs and SNAPs (Soluble NSF Attachment Proteins) on target (cell surface) membranes, with SM (Sec1/Munc18like) accessory proteins acting as catalysts for fusion (2). Human Syntaxin 4 cDNA encodes 297 amino acids (aa) including basolateral targeting motif for epithelial cells (aa2429), a coiledcoil domain termed Habc (aa43163), an Snitrosylation site which regulates fusion (aa141), a hinge region, a tSNARE domain (aa 200262), and a Cterminal transmembrane domain (aa276296) (14). Within aa1183, human Syntaxin 4 shares 89% aa sequence homology with mouse and rat, and 9495% wit |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q12846 |
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| Catalog # | 145836 |
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| Order / More Info | Syntaxin 4, Recombinant, Human, aa1-183 (NY-REN-31, p35-2, STX4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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