| 产品详情 |
| Edit |   |
|---|
| Product Name | Ren2, Recombinant, Mouse, aa64-351, His-Tag (Renin-2) |
|---|
| Description | Purity ~90% (SDS-PAGE). Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Its other ligands include G protein-coupled receptor 1 (GPR1) and chemokine receptor-like 2 (CCRL2). Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. Also acts as a proinflammatory adipokine, causing an increase in secretion of proinflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systemic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues. Can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. Acts as a chemotactic facto |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Chemerin RAR-responsive protein,TIG2, Tazarotene-induced gene 2 protein |
|---|
| Gene, Accession, CAS # | SwissProt: P00796 |
|---|
| Catalog # | 375035 |
|---|
| Price | |
|---|
| Order / More Info | Ren2, Recombinant, Mouse, aa64-351, His-Tag (Renin-2) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|