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| Product Name | IL-21 BioAssay™ ELISA Kit, Mouse |
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| Description | Sandwich ELISA quantitative detection kit for Mouse IL-21 in cell culture supernates and serum. Interleukin-21 is a protein that in humans is encoded by the IL21 gene. Interleukin 21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. By radiation hybrid analysis, the IL21 gene is mapped to chromosome 4q26-q27, near the IL2 gene. IL21 stimulates B-cell proliferation in an anti-CD40-dependent manner but inhibits proliferation stimulated by IL4 plus anti-IgM. The biologic effects of IL21 on NK cells differ between species, with human IL21 enhancing NK cell proliferation and murine IL21 inhibiting NK cell proliferation. IL21 is a cytokine highly expressed by mouse T(H)17 cells. Assay Range: 62.5pg/ml-4000pg/ml Sensitivity: < 10 pg/ml Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: Q5SUE2 Entrez Gene I |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 60505, SwissProt: Q5SUE2 |
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| Catalog # | 143910 |
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| Order / More Info | IL-21 BioAssay™ ELISA Kit, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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