| 产品详情 |
| Edit |   |
| Product Name | IL-36beta, Recombinant, Human (Interleukin-36beta, Interleukin-1 Family Member 8, IL-1F8) |
| Description | Purity >95% (SDS-PAGE). IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. Sequence: IL-36beta (human) (aa 5-157) (isoform 2) is untagged. |
| Size | 10ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Interleukin-36beta, Interleukin-1 Family Member 8, IL-1F8 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 44939 |
| Price | |
| Order / More Info | IL-36beta, Recombinant, Human (Interleukin-36beta, Interleukin-1 Family Member 8, IL-1F8) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
| 产品资料 |
|
|