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| Product Name | Renin Activity Fluorometric BioAssay™ Kit (Angiotensinogenase) |
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| Description | Renin (EC 3.4.23.15), also known as an angiotensinogenase, is an enzyme that participates in the renin-angiotensin system (RAS) which mediates extracellular volume (i.e. blood plasma, lymph and interstitial fluid) and arterial vasoconstriction. An over-active renin-angiotensin system leads to vasoconstriction and retention of sodium and water, causing hypertension. Renin inhibitors are widely used for the treatment of hypertension. Sample Type: Recombinant purified protein Intended Use: Detects Renin Activity in samples containing renin. Sensitivity: The assay can detect renin activity as low as 0.75U/ml. Test Principle: The Renin Activity BioAssay™ Kit, Renin and other proteases hydrolyze the FRET substrate resulting in a product that is detected fluorometrically at Ex/Em=328/552nm to give total protease activity. In the presence of a Renin-Specific Inhibitor, hydrolysis of the substrate is only due to the non-specific protease activity. The difference between the total activity |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 220227 |
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| Order / More Info | Renin Activity Fluorometric BioAssay™ Kit (Angiotensinogenase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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