| 产品详情 |
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| Product Name | HMTase Inhibitor IV, UNC0638 |
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| Description | Purity ~99% (HPLC). A cell-permeable quinazolinamine compound that acts as a potent and reversible inhibitor of G9a and GLP HMTases (histone methyltransferases) (IC50=10uM). Shown to lower H3K9Me2 levels in MDA-MB231 cells (IC50=81nM; EC50=11.2uM for cell toxicity) and 6-fold more potent than the HMTase Inhibitor, BIX-01294. Also, affects the activities of adrenergic a1A, adrenergic a and muscarinicM2 by 90%, 69% and 64% and a panel of 26-receptors and ion-channels by <30% at 1uM. Formula: C30H47N5O2 Molecular Weight: 509.7 Solubility: DMSO (100mg/ml, clear, nearly colorless solution) |
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| Size | 2mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HMTase Inhibitor IV, UNC0638 (2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217433 |
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| Order / More Info | HMTase Inhibitor IV, UNC0638 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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