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| Product Name | Thrombospondin Type-1 Domain-containing Protein 1, Recombinant, Mouse |
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| Description | Purity ≥90%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.Endotoxin: ≤1EU/ug protein (LAL). Mouse THSD1 (Thrombospondin type-1 domain-containing protein 1), also known as Transmembrane molecule with thrombospondin module (Tmtsp), is a 95kD, type I transmembrane protein (1). It is synthesized as a precursor that is 851 amino acids (aa) in length, and has a 24 aa signal sequence, a 388 aa extracellular region, a 21 aa transmembrane region, and a 418 aa cytoplasmic region. The extracellular region contains six potential N-linked glycosylation sites and the thrombospondin type-1 (TSP1) domain, which is implicated in cell adhesion and migration (1). Also present in the molecule are 9 PKC-phosphorylation sites, 3 Ig-like domains, and a tyrosine-phosphorylation site by its C-terminus (1). Mouse THSD1 shares 78% aa sequence identity with human THSD1. THSD1 is highly expressed in hematopoietic stem cells (HSCs) and progenitor cells, including CD34-/lowKit+ |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | Thrombospondin Type-1 Domain-containing Protein 1, Recombinant, Mouse (THSD1, Transmembrane Molecule with Thrombospondin Module, Tmtsp) |
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| Gene, Accession, CAS # | SwissProt: Q9JM61 |
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| Catalog # | T5101-10 |
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| Order / More Info | Thrombospondin Type-1 Domain-containing Protein 1, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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