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| Product Name | Thrombospondin, Human |
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| Description | Purity ~95% (SDS-PAGE). Thrombospondin is a high-molecular weight, heparin-binding glycoprotein constituent of human platelets. Ranging from 30-50ug per 109 platelets, thrombospondin is one of the most abundant proteins in the platelet a-granule. Thrombospondin was initially termed thrombin-sensitive protein based upon its release by thrombin-activated platelets. Structurally, thrombospondin is a 450,000 MW glycoprotein consisting of three, identical, disulfide-linked polypeptide chains. The binding of thrombospondin to the surface of both resting and thrombin-activated platelets has been reported. A thrombospondin-specific membrane receptor has also been partially characterized. Functionally, platelet-derived thrombospondin may play a role in platelet adherence and aggregation. Thrombospondin is not an exclusive product of platelets and megakaryoctes. The synthesis of thrombospondin by endothelial cells, fibroblasts, monocytes and macrophages, and osteoblasts has been reported. Thro |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T5110-01 |
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| Order / More Info | Thrombospondin, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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